Nucleoside Metabolic Inhibitor [EPC]: Side Effects & Safety Data for 12 Drugs
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Nucleoside Metabolic Inhibitor [EPC] includes 12 drugs with a combined 252,500 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
12
Drugs in Class
252,500
Combined Reports
All Nucleoside Metabolic Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| CAPECITABINE | Capecitabine | 63,506 | 8,892 | 17,529 | 14.0% |
| FLUOROURACIL | FLUOROURACIL | 53,045 | 6,997 | 20,941 | 13.2% |
| CYTARABINE | cytarabine | 44,383 | 9,089 | 17,861 | 20.5% |
| GEMCITABINE | Gemcitabine | 31,328 | 5,142 | 12,268 | 16.4% |
| FLUDARABINE | Fludarabine Phosphate | 23,660 | 6,831 | 6,745 | 28.9% |
| AZACITIDINE | Azacitidine | 19,323 | 6,641 | 9,028 | 34.4% |
| MERCAPTOPURINE | Mercaptopurine | 11,490 | 1,468 | 5,925 | 12.8% |
| DECITABINE | Decitabine | 2,983 | 816 | 1,060 | 27.4% |
| CLOFARABINE | Clofarabine | 1,419 | 528 | 409 | 37.2% |
| NELARABINE | Nelarabine | 735 | 156 | 265 | 21.2% |
| PENTOSTATIN | Nipent | 455 | 109 | 121 | 24.0% |
| TRIFLURIDINE | Trifluridine | 173 | 26 | 34 | 15.0% |
Common Side Effects in Nucleoside Metabolic Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Off label use | 18,982 | 3,589 |
| Diarrhoea | 18,545 | 2,346 |
| Febrile neutropenia | 16,902 | 2,833 |
| Nausea | 14,357 | 1,451 |
| Neutropenia | 14,141 | 2,513 |
| Disease progression | 13,071 | 3,255 |
| Drug ineffective | 11,957 | 2,866 |
| Pyrexia | 11,845 | 1,795 |
| Thrombocytopenia | 11,118 | 1,959 |
| Death | 10,931 | 10,842 |