Nucleoside Metabolic Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Off label use | 18,982 | 12 | 3,589 | 5,643 | 1,614 |
| Diarrhoea | 18,545 | 12 | 2,346 | 8,085 | 1,186 |
| Febrile neutropenia | 16,902 | 12 | 2,833 | 10,745 | 2,740 |
| Nausea | 14,357 | 12 | 1,451 | 5,681 | 630 |
| Neutropenia | 14,141 | 12 | 2,513 | 4,731 | 1,649 |
| Disease progression | 13,071 | 12 | 3,255 | 1,992 | 418 |
| Drug ineffective | 11,957 | 12 | 2,866 | 2,951 | 985 |
| Pyrexia | 11,845 | 11 | 1,795 | 8,130 | 1,161 |
| Thrombocytopenia | 11,118 | 12 | 1,959 | 4,115 | 1,471 |
| Death | 10,931 | 12 | 10,842 | 1,079 | 269 |
| Vomiting | 10,569 | 12 | 1,381 | 5,522 | 652 |
| Fatigue | 10,115 | 12 | 1,154 | 3,371 | 313 |
| Anaemia | 8,816 | 12 | 1,402 | 3,827 | 984 |
| Malignant neoplasm progression | 7,286 | 10 | 1,978 | 1,499 | 281 |
| Sepsis | 6,983 | 11 | 3,385 | 3,976 | 1,381 |
| Pneumonia | 6,940 | 11 | 2,855 | 3,955 | 1,034 |
| Myelosuppression | 6,670 | 10 | 375 | 3,051 | 878 |
| Asthenia | 6,586 | 11 | 976 | 3,141 | 365 |
| Palmar-plantar erythrodysaesthesia syndrome | 6,521 | 9 | 425 | 1,149 | 208 |
| Neuropathy peripheral | 6,517 | 11 | 516 | 1,205 | 205 |
| Product use in unapproved indication | 6,012 | 11 | 1,222 | 1,434 | 418 |
| Mucosal inflammation | 5,792 | 9 | 1,030 | 2,406 | 729 |
| Decreased appetite | 5,625 | 10 | 776 | 2,405 | 353 |
| Pancytopenia | 5,557 | 11 | 1,314 | 2,915 | 774 |
| Abdominal pain | 4,881 | 9 | 726 | 2,919 | 337 |
| Dyspnoea | 4,794 | 11 | 981 | 2,777 | 377 |
| Acute kidney injury | 4,728 | 11 | 1,154 | 3,177 | 797 |
| Platelet count decreased | 4,609 | 11 | 677 | 2,345 | 606 |
| Infection | 4,350 | 11 | 1,849 | 1,627 | 293 |
| Rash | 4,327 | 10 | 457 | 1,184 | 225 |