Malignant neoplasm progression: Which Medications Cause It? (82,343 Reports Across 771 Drugs)
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Malignant neoplasm progression has been reported as an adverse event with 771 different drugs in the FDA's FAERS database, with 82,343 total reports. 29,275 of these reports resulted in death.The drugs most commonly associated with Malignant neoplasm progression are PEMBROLIZUMAB, NIVOLUMAB, and ENZALUTAMIDE.
82,343
Total Reports
771
Drugs Involved
29,275
Deaths
20,493
Hospitalizations
61.6 yrs
Average Patient Age
50.3% / 49.7%
Female / Male
Which Drugs Cause Malignant neoplasm progression Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PEMBROLIZUMAB | 10,111 | 12.1% | 5,124 | 3,426 | 610 |
| NIVOLUMAB | 9,363 | 10.7% | 5,146 | 4,330 | 797 |
| ENZALUTAMIDE | 4,696 | 9.5% | 1,482 | 695 | 32 |
| CARBOPLATIN | 4,177 | 5.0% | 1,068 | 971 | 199 |
| EVEROLIMUS | 3,789 | 9.6% | 1,120 | 1,076 | 141 |
| PACLITAXEL | 3,484 | 4.5% | 916 | 760 | 155 |
| LETROZOLE | 3,445 | 11.1% | 506 | 517 | 108 |
| IPILIMUMAB | 3,296 | 9.0% | 1,570 | 1,538 | 280 |
| FULVESTRANT | 3,221 | 18.2% | 486 | 402 | 81 |
| LENVATINIB | 2,929 | 8.7% | 1,549 | 1,298 | 143 |
| OSIMERTINIB | 2,920 | 10.5% | 574 | 354 | 74 |
| CABOZANTINIB S-MALATE | 2,718 | 6.9% | 909 | 626 | 61 |
| CYCLOPHOSPHAMIDE | 2,568 | 2.0% | 759 | 434 | 137 |
| RIBOCICLIB | 2,468 | 8.8% | 683 | 585 | 116 |
| CAPECITABINE | 2,425 | 3.8% | 461 | 403 | 54 |
| OCTREOTIDE | 2,306 | 9.7% | 610 | 1,109 | 95 |
| DOCETAXEL | 2,199 | 3.4% | 609 | 344 | 57 |
| DOXORUBICIN | 2,193 | 2.7% | 605 | 342 | 119 |
| PEMETREXED | 2,149 | 9.1% | 613 | 587 | 93 |
| CISPLATIN | 2,004 | 4.2% | 726 | 446 | 79 |