Does ACETAMINOPHEN Cause Necrosis? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Necrosis have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 0.0% of all adverse event reports for ACETAMINOPHEN.
41
Reports of Necrosis with ACETAMINOPHEN
0.0%
of all ACETAMINOPHEN reports
19
Deaths
27
Hospitalizations
How Dangerous Is Necrosis From ACETAMINOPHEN?
Of the 41 reports, 19 (46.3%) resulted in death, 27 (65.9%) required hospitalization, and 2 (4.9%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which ACETAMINOPHEN Alternatives Have Lower Necrosis Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM