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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does ACETAMINOPHEN Cause Splenomegaly? 111 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 111 reports of Splenomegaly have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 0.1% of all adverse event reports for ACETAMINOPHEN.

111
Reports of Splenomegaly with ACETAMINOPHEN
0.1%
of all ACETAMINOPHEN reports
10
Deaths
65
Hospitalizations

How Dangerous Is Splenomegaly From ACETAMINOPHEN?

Of the 111 reports, 10 (9.0%) resulted in death, 65 (58.6%) required hospitalization, and 39 (35.1%) were considered life-threatening.

Is Splenomegaly Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 111 reports have been filed with the FAERS database.

What Other Side Effects Does ACETAMINOPHEN Cause?

Drug ineffective (17,522) Toxicity to various agents (16,128) Off label use (9,410) Vomiting (9,055) Pain (8,573) Fatigue (8,202) Overdose (7,917) Nausea (7,245) Rash (7,107) Headache (7,084)

What Other Drugs Cause Splenomegaly?

RUXOLITINIB (1,995) RITUXIMAB (326) PREDNISONE (299) IBRUTINIB (279) CYCLOPHOSPHAMIDE (254) METHOTREXATE (253) OXALIPLATIN (253) ADALIMUMAB (245) TACROLIMUS (218) IMATINIB (216)

Which ACETAMINOPHEN Alternatives Have Lower Splenomegaly Risk?

ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM

Related Pages

ACETAMINOPHEN Full Profile All Splenomegaly Reports All Drugs Causing Splenomegaly ACETAMINOPHEN Demographics