Does ACETAMINOPHEN\CODEINE Cause Hepatic cytolysis? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Hepatic cytolysis have been filed in association with ACETAMINOPHEN\CODEINE. This represents 0.5% of all adverse event reports for ACETAMINOPHEN\CODEINE.
79
Reports of Hepatic cytolysis with ACETAMINOPHEN\CODEINE
0.5%
of all ACETAMINOPHEN\CODEINE reports
14
Deaths
58
Hospitalizations
How Dangerous Is Hepatic cytolysis From ACETAMINOPHEN\CODEINE?
Of the 79 reports, 14 (17.7%) resulted in death, 58 (73.4%) required hospitalization, and 12 (15.2%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN\CODEINE. However, 79 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN\CODEINE Cause?
Dependence (3,857)
Overdose (2,600)
Pain (1,712)
Off label use (1,309)
Drug ineffective (1,300)
Nausea (1,291)
Drug dependence (1,273)
Fatigue (1,240)
Vomiting (1,224)
Depression (1,153)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which ACETAMINOPHEN\CODEINE Alternatives Have Lower Hepatic cytolysis Risk?
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE\DOXYLAMINE
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE\DOXYLAMINE\PHENYLEPHRINE
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE\GUAIFENESIN\PHENYLEPHRINE
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE\PHENYLEPHRINE