Does ADAGRASIB Cause Hepatic cytolysis? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatic cytolysis have been filed in association with ADAGRASIB (KRAZATI). This represents 1.2% of all adverse event reports for ADAGRASIB.
11
Reports of Hepatic cytolysis with ADAGRASIB
1.2%
of all ADAGRASIB reports
3
Deaths
7
Hospitalizations
How Dangerous Is Hepatic cytolysis From ADAGRASIB?
Of the 11 reports, 3 (27.3%) resulted in death, 7 (63.6%) required hospitalization, and 3 (27.3%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ADAGRASIB. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does ADAGRASIB Cause?
Death (272)
Diarrhoea (113)
Hospitalisation (108)
Nausea (87)
Vomiting (79)
Off label use (70)
Asthenia (61)
Fatigue (51)
Decreased appetite (43)
Dehydration (35)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which ADAGRASIB Alternatives Have Lower Hepatic cytolysis Risk?
ADAGRASIB vs ADALIMUMAB
ADAGRASIB vs ADALIMUMAB-AACF
ADAGRASIB vs ADALIMUMAB-AATY
ADAGRASIB vs ADALIMUMAB-ADAZ
ADAGRASIB vs ADALIMUMAB-ADBM