AFATINIB for K-ras gene mutation: Side Effects & Safety Data

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There are 5 adverse event reports in the FDA FAERS database where AFATINIB was used for K-ras gene mutation.

Most Reported Side Effects for AFATINIB

Side Effect	Reports	%	Deaths	Hosp.
Diarrhoea	2,001	32.9%	351	984
Malignant neoplasm progression	1,622	26.7%	445	283
Rash	808	13.3%	131	315
Stomatitis	468	7.7%	77	234
Death	443	7.3%	443	63
Nausea	430	7.1%	69	280
Decreased appetite	412	6.8%	85	255
Vomiting	381	6.3%	67	271
Paronychia	344	5.7%	62	133
Dehydration	323	5.3%	56	276
Fatigue	256	4.2%	52	128
Metastases to central nervous system	248	4.1%	72	58
Asthenia	221	3.6%	46	151
Off label use	204	3.4%	64	37
Drug ineffective	203	3.3%	31	47