Does ALTEPLASE Cause Leg amputation? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Leg amputation have been filed in association with ALTEPLASE (Activase). This represents 0.1% of all adverse event reports for ALTEPLASE.
8
Reports of Leg amputation with ALTEPLASE
0.1%
of all ALTEPLASE reports
2
Deaths
2
Hospitalizations
How Dangerous Is Leg amputation From ALTEPLASE?
Of the 8 reports, 2 (25.0%) resulted in death, 2 (25.0%) required hospitalization.
Is Leg amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Leg amputation?
CANAGLIFLOZIN (792)
INSULIN GLARGINE (157)
ADALIMUMAB (93)
METFORMIN (79)
EMPAGLIFLOZIN (67)
OXYCODONE (67)
CANAGLIFLOZIN\METFORMIN (62)
RIVAROXABAN (58)
INSULIN ASPART (49)
ETANERCEPT (43)
Which ALTEPLASE Alternatives Have Lower Leg amputation Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE