Does AMIKACIN Cause Hypertransaminasaemia? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Hypertransaminasaemia have been filed in association with AMIKACIN (ARIKAYCE). This represents 0.4% of all adverse event reports for AMIKACIN.
49
Reports of Hypertransaminasaemia with AMIKACIN
0.4%
of all AMIKACIN reports
12
Deaths
20
Hospitalizations
How Dangerous Is Hypertransaminasaemia From AMIKACIN?
Of the 49 reports, 12 (24.5%) resulted in death, 20 (40.8%) required hospitalization, and 14 (28.6%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMIKACIN. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does AMIKACIN Cause?
Cough (1,472)
Off label use (1,447)
Dyspnoea (1,367)
Hospitalisation (1,325)
Therapy interrupted (1,283)
Drug ineffective (1,275)
Death (1,005)
Dysphonia (914)
Product dose omission issue (677)
Fatigue (602)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which AMIKACIN Alternatives Have Lower Hypertransaminasaemia Risk?
AMIKACIN vs AMILORIDE
AMIKACIN vs AMILORIDE\HYDROCHLOROTHIAZIDE
AMIKACIN vs AMINO ACIDS
AMIKACIN vs AMINO ACIDS, SOURCE UNSPECIFIED
AMIKACIN vs AMINO ACIDS\ANHYDROUS DEXTROSE\CALCIUM\MAGNESIUM HEPTAHYDRATE\POTASSIUM\SODIUM\SODIUM GLYCEROPHOSPHATE ANHYDROUS\SOYBEAN OIL