Does APREMILAST Cause Liver injury? 1,358 Reports in FDA Database

Q: Does APREMILAST cause Liver injury?

1,358 reports of Liver injury have been filed with the FDA for APREMILAST, representing 1.0% of all APREMILAST adverse event reports.

Q: How dangerous is Liver injury from APREMILAST?

Of 1,358 reports, 1,166 (85.9%) resulted in death and 1,043 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 1,358 reports of Liver injury have been filed in association with APREMILAST (Otezla). This represents 1.0% of all adverse event reports for APREMILAST.

1,358

Reports of Liver injury with APREMILAST

1.0%

of all APREMILAST reports

1,166

Deaths

1,043

Hospitalizations

How Dangerous Is Liver injury From APREMILAST?

Of the 1,358 reports, 1,166 (85.9%) resulted in death, 1,043 (76.8%) required hospitalization, and 1,135 (83.6%) were considered life-threatening.

Is Liver injury Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 1,358 reports have been filed with the FAERS database.

What Other Side Effects Does APREMILAST Cause?

Diarrhoea (23,752) Nausea (21,352) Psoriasis (19,255) Headache (17,024) Drug ineffective (14,121) Abdominal discomfort (7,653) Psoriatic arthropathy (7,035) Vomiting (5,959) Rash (5,883) Pain (5,676)

What Other Drugs Cause Liver injury?

METHOTREXATE (3,601) ACETAMINOPHEN (3,002) RITUXIMAB (2,692) TOCILIZUMAB (2,637) ADALIMUMAB (2,635) PREDNISONE (2,611) LEFLUNOMIDE (2,574) ABATACEPT (2,572) HYDROXYCHLOROQUINE (2,528) DICLOFENAC (2,487)

Which APREMILAST Alternatives Have Lower Liver injury Risk?

APREMILAST vs APREPITANT APREMILAST vs APROTININ APREMILAST vs ARANESP APREMILAST vs ARAVA APREMILAST vs AREDIA

APREMILAST Full Profile All Liver injury Reports All Drugs Causing Liver injury APREMILAST Demographics