Does ASPARAGINASE Cause Myelopathy? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Myelopathy have been filed in association with ASPARAGINASE (Rylaze). This represents 0.2% of all adverse event reports for ASPARAGINASE.
12
Reports of Myelopathy with ASPARAGINASE
0.2%
of all ASPARAGINASE reports
4
Deaths
3
Hospitalizations
How Dangerous Is Myelopathy From ASPARAGINASE?
Of the 12 reports, 4 (33.3%) resulted in death, 3 (25.0%) required hospitalization, and 2 (16.7%) were considered life-threatening.
Is Myelopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Myelopathy?
METHOTREXATE (352)
CYTARABINE (185)
BUPRENORPHINE (80)
RITUXIMAB (79)
DEXAMETHASONE (73)
VINCRISTINE (60)
PREDNISOLONE (57)
PREDNISONE (57)
CYCLOPHOSPHAMIDE (51)
NELARABINE (47)
Which ASPARAGINASE Alternatives Have Lower Myelopathy Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE