Does ASPARAGINASE Cause Pancytopenia? 102 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 102 reports of Pancytopenia have been filed in association with ASPARAGINASE (Rylaze). This represents 2.0% of all adverse event reports for ASPARAGINASE.
102
Reports of Pancytopenia with ASPARAGINASE
2.0%
of all ASPARAGINASE reports
36
Deaths
51
Hospitalizations
How Dangerous Is Pancytopenia From ASPARAGINASE?
Of the 102 reports, 36 (35.3%) resulted in death, 51 (50.0%) required hospitalization, and 6 (5.9%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 102 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which ASPARAGINASE Alternatives Have Lower Pancytopenia Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE