Does BEVACIZUMAB Cause Cholangitis? 176 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 176 reports of Cholangitis have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.2% of all adverse event reports for BEVACIZUMAB.
176
Reports of Cholangitis with BEVACIZUMAB
0.2%
of all BEVACIZUMAB reports
40
Deaths
92
Hospitalizations
How Dangerous Is Cholangitis From BEVACIZUMAB?
Of the 176 reports, 40 (22.7%) resulted in death, 92 (52.3%) required hospitalization, and 7 (4.0%) were considered life-threatening.
Is Cholangitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BEVACIZUMAB. However, 176 reports have been filed with the FAERS database.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
PACLITAXEL (289)
GEMCITABINE (225)
TACROLIMUS (213)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
ATEZOLIZUMAB (145)
Which BEVACIZUMAB Alternatives Have Lower Cholangitis Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ