Cholangitis: Which Medications Cause It? (4,346 Reports Across 285 Drugs)
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Cholangitis has been reported as an adverse event with 285 different drugs in the FDA's FAERS database, with 4,346 total reports. 684 of these reports resulted in death.The drugs most commonly associated with Cholangitis are NIVOLUMAB, PEMBROLIZUMAB, and PACLITAXEL.
4,346
Total Reports
285
Drugs Involved
684
Deaths
2,713
Hospitalizations
62.3 yrs
Average Patient Age
42.5% / 57.5%
Female / Male
Which Drugs Cause Cholangitis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 389 | 0.4% | 50 | 223 | 14 |
| PEMBROLIZUMAB | 357 | 0.4% | 38 | 212 | 14 |
| PACLITAXEL | 289 | 0.4% | 43 | 177 | 22 |
| GEMCITABINE | 225 | 0.7% | 38 | 140 | 17 |
| TACROLIMUS | 213 | 0.2% | 51 | 101 | 11 |
| BEVACIZUMAB | 176 | 0.2% | 40 | 92 | 7 |
| FLUOROURACIL | 175 | 0.3% | 37 | 125 | 6 |
| DURVALUMAB | 157 | 0.9% | 33 | 55 | 12 |
| OXALIPLATIN | 147 | 0.3% | 27 | 97 | 4 |
| IRINOTECAN | 146 | 0.5% | 31 | 98 | 6 |
| ATEZOLIZUMAB | 145 | 0.4% | 27 | 80 | 7 |
| LENVATINIB | 138 | 0.4% | 21 | 86 | 2 |
| CARBOPLATIN | 137 | 0.2% | 12 | 92 | 5 |
| MYCOPHENOLATE MOFETIL | 132 | 0.2% | 34 | 42 | 3 |
| CISPLATIN | 131 | 0.3% | 14 | 58 | 7 |
| PREDNISOLONE | 121 | 0.2% | 25 | 61 | 10 |
| GEMCITABINE\GEMCITABINE | 114 | 1.1% | 16 | 57 | 7 |
| LEUCOVORIN | 114 | 0.5% | 24 | 84 | 5 |
| ADALIMUMAB | 111 | 0.0% | 9 | 63 | 2 |
| EVEROLIMUS | 93 | 0.2% | 15 | 43 | 5 |