Does PACLITAXEL Cause Cholangitis? 289 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 289 reports of Cholangitis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
289
Reports of Cholangitis with PACLITAXEL
0.4%
of all PACLITAXEL reports
43
Deaths
177
Hospitalizations
How Dangerous Is Cholangitis From PACLITAXEL?
Of the 289 reports, 43 (14.9%) resulted in death, 177 (61.2%) required hospitalization, and 22 (7.6%) were considered life-threatening.
Is Cholangitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 289 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
GEMCITABINE (225)
TACROLIMUS (213)
BEVACIZUMAB (176)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
ATEZOLIZUMAB (145)
Which PACLITAXEL Alternatives Have Lower Cholangitis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON