Does LEUCOVORIN Cause Cholangitis? 114 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 114 reports of Cholangitis have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.5% of all adverse event reports for LEUCOVORIN.
114
Reports of Cholangitis with LEUCOVORIN
0.5%
of all LEUCOVORIN reports
24
Deaths
84
Hospitalizations
How Dangerous Is Cholangitis From LEUCOVORIN?
Of the 114 reports, 24 (21.1%) resulted in death, 84 (73.7%) required hospitalization, and 5 (4.4%) were considered life-threatening.
Is Cholangitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 114 reports have been filed with the FAERS database.
What Other Side Effects Does LEUCOVORIN Cause?
Diarrhoea (2,594)
Neutropenia (2,291)
Nausea (1,977)
Neuropathy peripheral (1,557)
Disease progression (1,456)
Fatigue (1,443)
Vomiting (1,441)
Off label use (1,390)
Thrombocytopenia (1,181)
Pyrexia (1,148)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
PACLITAXEL (289)
GEMCITABINE (225)
TACROLIMUS (213)
BEVACIZUMAB (176)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
Which LEUCOVORIN Alternatives Have Lower Cholangitis Risk?
LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN
LEUCOVORIN vs LEUPROLIDE
LEUCOVORIN vs LEVALBUTEROL
LEUCOVORIN vs LEVAMISOLE
LEUCOVORIN vs LEVAQUIN