Does BINIMETINIB Cause Hepatic failure? 13 Reports in FDA Database

Q: Does BINIMETINIB cause Hepatic failure?

13 reports of Hepatic failure have been filed with the FDA for BINIMETINIB, representing 0.2% of all BINIMETINIB adverse event reports.

Q: How dangerous is Hepatic failure from BINIMETINIB?

Of 13 reports, 5 (38.5%) resulted in death and 7 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hepatic failure have been filed in association with BINIMETINIB (MEKTOVI). This represents 0.2% of all adverse event reports for BINIMETINIB.

Reports of Hepatic failure with BINIMETINIB

0.2%

of all BINIMETINIB reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From BINIMETINIB?

Of the 13 reports, 5 (38.5%) resulted in death, 7 (53.8%) required hospitalization, and 1 (7.7%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 13 reports have been filed with the FAERS database.

What Other Side Effects Does BINIMETINIB Cause?

Off label use (902) Death (719) Nausea (657) Fatigue (562) Diarrhoea (521) Product use in unapproved indication (508) Pyrexia (490) Neoplasm progression (387) Vomiting (375) Rash (360)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which BINIMETINIB Alternatives Have Lower Hepatic failure Risk?

BINIMETINIB vs BIOFLAVONOIDS BINIMETINIB vs BIOTIN BINIMETINIB vs BIPERIDEN BINIMETINIB vs BIRCH TRITERPENES BINIMETINIB vs BISACODYL

BINIMETINIB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure BINIMETINIB Demographics