Does BORTEZOMIB Cause Necrosis? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Necrosis have been filed in association with BORTEZOMIB (bortezomib). This represents 0.1% of all adverse event reports for BORTEZOMIB.
23
Reports of Necrosis with BORTEZOMIB
0.1%
of all BORTEZOMIB reports
10
Deaths
19
Hospitalizations
How Dangerous Is Necrosis From BORTEZOMIB?
Of the 23 reports, 10 (43.5%) resulted in death, 19 (82.6%) required hospitalization, and 6 (26.1%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BORTEZOMIB. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does BORTEZOMIB Cause?
Plasma cell myeloma (6,683)
Off label use (4,754)
Neuropathy peripheral (4,067)
Drug ineffective (2,730)
Diarrhoea (2,244)
Thrombocytopenia (2,082)
Death (2,025)
Pneumonia (2,020)
Fatigue (1,757)
Neutropenia (1,530)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which BORTEZOMIB Alternatives Have Lower Necrosis Risk?
BORTEZOMIB vs BOSENTAN
BORTEZOMIB vs BOSENTAN\BOSENTAN
BORTEZOMIB vs BOSULIF
BORTEZOMIB vs BOSUTINIB
BORTEZOMIB vs BOTOX