Does BUPRENORPHINE Cause Depression? 1,868 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,868 reports of Depression have been filed in association with BUPRENORPHINE (Buprenorphine and Naloxone). This represents 2.3% of all adverse event reports for BUPRENORPHINE.
1,868
Reports of Depression with BUPRENORPHINE
2.3%
of all BUPRENORPHINE reports
557
Deaths
600
Hospitalizations
How Dangerous Is Depression From BUPRENORPHINE?
Of the 1,868 reports, 557 (29.8%) resulted in death, 600 (32.1%) required hospitalization, and 377 (20.2%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for BUPRENORPHINE.
What Other Side Effects Does BUPRENORPHINE Cause?
Drug dependence (16,730)
Overdose (13,977)
Death (13,604)
Toxicity to various agents (10,906)
Pain (8,219)
Drug withdrawal syndrome (7,149)
Emotional distress (6,159)
Drug abuse (4,344)
Drug ineffective (4,261)
Dependence (3,184)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which BUPRENORPHINE Alternatives Have Lower Depression Risk?
BUPRENORPHINE vs BUPRENORPHINE\NALOXONE
BUPRENORPHINE vs BUPROPION
BUPRENORPHINE vs BUPROPION HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\NALTREXONE