Does BUPRENORPHINE Cause Osteoarthritis? 454 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 454 reports of Osteoarthritis have been filed in association with BUPRENORPHINE (Buprenorphine and Naloxone). This represents 0.6% of all adverse event reports for BUPRENORPHINE.
454
Reports of Osteoarthritis with BUPRENORPHINE
0.6%
of all BUPRENORPHINE reports
426
Deaths
357
Hospitalizations
How Dangerous Is Osteoarthritis From BUPRENORPHINE?
Of the 454 reports, 426 (93.8%) resulted in death, 357 (78.6%) required hospitalization, and 359 (79.1%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPRENORPHINE. However, 454 reports have been filed with the FAERS database.
What Other Side Effects Does BUPRENORPHINE Cause?
Drug dependence (16,730)
Overdose (13,977)
Death (13,604)
Toxicity to various agents (10,906)
Pain (8,219)
Drug withdrawal syndrome (7,149)
Emotional distress (6,159)
Drug abuse (4,344)
Drug ineffective (4,261)
Dependence (3,184)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which BUPRENORPHINE Alternatives Have Lower Osteoarthritis Risk?
BUPRENORPHINE vs BUPRENORPHINE\NALOXONE
BUPRENORPHINE vs BUPROPION
BUPRENORPHINE vs BUPROPION HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\NALTREXONE