Does BUSULFAN Cause Hepatic failure? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Hepatic failure have been filed in association with BUSULFAN (Busulfan). This represents 1.1% of all adverse event reports for BUSULFAN.
121
Reports of Hepatic failure with BUSULFAN
1.1%
of all BUSULFAN reports
89
Deaths
46
Hospitalizations
How Dangerous Is Hepatic failure From BUSULFAN?
Of the 121 reports, 89 (73.6%) resulted in death, 46 (38.0%) required hospitalization, and 14 (11.6%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUSULFAN. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Graft versus host disease (507)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which BUSULFAN Alternatives Have Lower Hepatic failure Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS