Does CAPECITABINE Cause Large intestine perforation? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Large intestine perforation have been filed in association with CAPECITABINE (Capecitabine). This represents 0.1% of all adverse event reports for CAPECITABINE.
55
Reports of Large intestine perforation with CAPECITABINE
0.1%
of all CAPECITABINE reports
11
Deaths
35
Hospitalizations
How Dangerous Is Large intestine perforation From CAPECITABINE?
Of the 55 reports, 11 (20.0%) resulted in death, 35 (63.6%) required hospitalization, and 17 (30.9%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CAPECITABINE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does CAPECITABINE Cause?
Diarrhoea (9,277)
Nausea (6,248)
Palmar-plantar erythrodysaesthesia syndrome (5,294)
Fatigue (5,018)
Death (4,422)
Vomiting (4,111)
Disease progression (3,808)
Off label use (3,193)
Malignant neoplasm progression (2,425)
Asthenia (2,352)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which CAPECITABINE Alternatives Have Lower Large intestine perforation Risk?
CAPECITABINE vs CAPIVASERTIB
CAPECITABINE vs CAPLACIZUMAB
CAPECITABINE vs CAPLACIZUMAB-YHDP
CAPECITABINE vs CAPMATINIB
CAPECITABINE vs CAPREOMYCIN