Does CARFILZOMIB Cause Polyneuropathy? 126 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 126 reports of Polyneuropathy have been filed in association with CARFILZOMIB (KYPROLIS). This represents 0.6% of all adverse event reports for CARFILZOMIB.
126
Reports of Polyneuropathy with CARFILZOMIB
0.6%
of all CARFILZOMIB reports
11
Deaths
12
Hospitalizations
How Dangerous Is Polyneuropathy From CARFILZOMIB?
Of the 126 reports, 11 (8.7%) resulted in death, 12 (9.5%) required hospitalization, and 3 (2.4%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CARFILZOMIB. However, 126 reports have been filed with the FAERS database.
What Other Side Effects Does CARFILZOMIB Cause?
Plasma cell myeloma (2,238)
Off label use (2,120)
Death (1,442)
Thrombocytopenia (1,265)
Fatigue (1,048)
Pneumonia (1,016)
Pyrexia (969)
Anaemia (910)
Dyspnoea (881)
Neutropenia (874)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which CARFILZOMIB Alternatives Have Lower Polyneuropathy Risk?
CARFILZOMIB vs CARGLUMIC ACID
CARFILZOMIB vs CARIPRAZINE
CARFILZOMIB vs CARISOPRODOL
CARFILZOMIB vs CARMUSTINE
CARFILZOMIB vs CARTEOLOL