Does CLOZAPINE Cause Hepatic failure? 50 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 50 reports of Hepatic failure have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.1% of all adverse event reports for CLOZAPINE.
50
Reports of Hepatic failure with CLOZAPINE
0.1%
of all CLOZAPINE reports
27
Deaths
28
Hospitalizations
How Dangerous Is Hepatic failure From CLOZAPINE?
Of the 50 reports, 27 (54.0%) resulted in death, 28 (56.0%) required hospitalization, and 11 (22.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 50 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which CLOZAPINE Alternatives Have Lower Hepatic failure Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL