Does COBIMETINIB Cause Hepatic cytolysis? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Hepatic cytolysis have been filed in association with COBIMETINIB (Cotellic). This represents 0.1% of all adverse event reports for COBIMETINIB.
5
Reports of Hepatic cytolysis with COBIMETINIB
0.1%
of all COBIMETINIB reports
0
Deaths
4
Hospitalizations
How Dangerous Is Hepatic cytolysis From COBIMETINIB?
Of the 5 reports, 4 (80.0%) required hospitalization.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which COBIMETINIB Alternatives Have Lower Hepatic cytolysis Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE