Does COBIMETINIB Cause Hyperbilirubinaemia? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Hyperbilirubinaemia have been filed in association with COBIMETINIB (Cotellic). This represents 0.3% of all adverse event reports for COBIMETINIB.
10
Reports of Hyperbilirubinaemia with COBIMETINIB
0.3%
of all COBIMETINIB reports
1
Deaths
5
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From COBIMETINIB?
Of the 10 reports, 1 (10.0%) resulted in death, 5 (50.0%) required hospitalization, and 1 (10.0%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which COBIMETINIB Alternatives Have Lower Hyperbilirubinaemia Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE