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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does COBIMETINIB Cause Hyperkeratosis? 23 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Hyperkeratosis have been filed in association with COBIMETINIB (Cotellic). This represents 0.6% of all adverse event reports for COBIMETINIB.

23
Reports of Hyperkeratosis with COBIMETINIB
0.6%
of all COBIMETINIB reports
2
Deaths
10
Hospitalizations

How Dangerous Is Hyperkeratosis From COBIMETINIB?

Of the 23 reports, 2 (8.7%) resulted in death, 10 (43.5%) required hospitalization, and 6 (26.1%) were considered life-threatening.

Is Hyperkeratosis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 23 reports have been filed with the FAERS database.

What Other Side Effects Does COBIMETINIB Cause?

Diarrhoea (412) Off label use (411) Rash (369) Pyrexia (332) Death (231) Nausea (206) Fatigue (198) No adverse event (178) Vomiting (168) Acute kidney injury (133)

What Other Drugs Cause Hyperkeratosis?

CABOZANTINIB S-MALATE (411) ADALIMUMAB (332) SUNITINIB MALATE (170) ETANERCEPT (168) SORAFENIB (150) METHOTREXATE (149) VEMURAFENIB (145) REGORAFENIB (136) RIPRETINIB (124) RITUXIMAB (121)

Which COBIMETINIB Alternatives Have Lower Hyperkeratosis Risk?

COBIMETINIB vs COCAETHYLENE COBIMETINIB vs COCAINE COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE COBIMETINIB vs COD LIVER OIL COBIMETINIB vs CODEINE

Related Pages

COBIMETINIB Full Profile All Hyperkeratosis Reports All Drugs Causing Hyperkeratosis COBIMETINIB Demographics