Does CODEINE Cause Acute hepatic failure? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Acute hepatic failure have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.2% of all adverse event reports for CODEINE.
35
Reports of Acute hepatic failure with CODEINE
0.2%
of all CODEINE reports
15
Deaths
26
Hospitalizations
How Dangerous Is Acute hepatic failure From CODEINE?
Of the 35 reports, 15 (42.9%) resulted in death, 26 (74.3%) required hospitalization, and 7 (20.0%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which CODEINE Alternatives Have Lower Acute hepatic failure Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE