Does CODEINE Cause Exostosis? 132 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 132 reports of Exostosis have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.6% of all adverse event reports for CODEINE.
132
Reports of Exostosis with CODEINE
0.6%
of all CODEINE reports
126
Deaths
117
Hospitalizations
How Dangerous Is Exostosis From CODEINE?
Of the 132 reports, 126 (95.5%) resulted in death, 117 (88.6%) required hospitalization, and 115 (87.1%) were considered life-threatening.
Is Exostosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 132 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Exostosis?
ADALIMUMAB (2,008)
METHOTREXATE (968)
ETANERCEPT (918)
ABATACEPT (775)
TOCILIZUMAB (768)
LEFLUNOMIDE (743)
SULFASALAZINE (712)
DICLOFENAC (702)
TOFACITINIB (702)
CERTOLIZUMAB PEGOL (695)
Which CODEINE Alternatives Have Lower Exostosis Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE