Does CODEINE\IBUPROFEN Cause Hepatic cytolysis? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Hepatic cytolysis have been filed in association with CODEINE\IBUPROFEN. This represents 21.6% of all adverse event reports for CODEINE\IBUPROFEN.
33
Reports of Hepatic cytolysis with CODEINE\IBUPROFEN
21.6%
of all CODEINE\IBUPROFEN reports
33
Deaths
20
Hospitalizations
How Dangerous Is Hepatic cytolysis From CODEINE\IBUPROFEN?
Of the 33 reports, 33 (100.0%) resulted in death, 20 (60.6%) required hospitalization, and 16 (48.5%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE\IBUPROFEN. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE\IBUPROFEN Cause?
Overdose (42)
Coma (33)
Cardio-respiratory arrest (27)
Myocarditis (27)
Toxicity to various agents (26)
Drug abuse (25)
Somnolence (25)
Intentional overdose (24)
Drug dependence (22)
Hyperglycaemia (22)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which CODEINE\IBUPROFEN Alternatives Have Lower Hepatic cytolysis Risk?
CODEINE\IBUPROFEN vs CODEINE\PROMETHAZINE
CODEINE\IBUPROFEN vs COLCHICINE
CODEINE\IBUPROFEN vs COLCHICINE\DICYCLOMINE
CODEINE\IBUPROFEN vs COLCHICINE\OPIUM\TIEMONIUM METHYLSULFATE
CODEINE\IBUPROFEN vs COLESEVELAM