Does CODEINE\IBUPROFEN Cause Hepatic failure? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Hepatic failure have been filed in association with CODEINE\IBUPROFEN. This represents 7.8% of all adverse event reports for CODEINE\IBUPROFEN.
12
Reports of Hepatic failure with CODEINE\IBUPROFEN
7.8%
of all CODEINE\IBUPROFEN reports
10
Deaths
5
Hospitalizations
How Dangerous Is Hepatic failure From CODEINE\IBUPROFEN?
Of the 12 reports, 10 (83.3%) resulted in death, 5 (41.7%) required hospitalization, and 4 (33.3%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE\IBUPROFEN. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE\IBUPROFEN Cause?
Overdose (42)
Coma (33)
Hepatic cytolysis (33)
Cardio-respiratory arrest (27)
Myocarditis (27)
Toxicity to various agents (26)
Drug abuse (25)
Somnolence (25)
Intentional overdose (24)
Drug dependence (22)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which CODEINE\IBUPROFEN Alternatives Have Lower Hepatic failure Risk?
CODEINE\IBUPROFEN vs CODEINE\PROMETHAZINE
CODEINE\IBUPROFEN vs COLCHICINE
CODEINE\IBUPROFEN vs COLCHICINE\DICYCLOMINE
CODEINE\IBUPROFEN vs COLCHICINE\OPIUM\TIEMONIUM METHYLSULFATE
CODEINE\IBUPROFEN vs COLESEVELAM