Does CRIZOTINIB Cause Hepatic cytolysis? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Hepatic cytolysis have been filed in association with CRIZOTINIB (Xalkori). This represents 0.2% of all adverse event reports for CRIZOTINIB.
21
Reports of Hepatic cytolysis with CRIZOTINIB
0.2%
of all CRIZOTINIB reports
1
Deaths
10
Hospitalizations
How Dangerous Is Hepatic cytolysis From CRIZOTINIB?
Of the 21 reports, 1 (4.8%) resulted in death, 10 (47.6%) required hospitalization, and 1 (4.8%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CRIZOTINIB. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does CRIZOTINIB Cause?
Death (2,028)
Neoplasm progression (1,161)
Nausea (820)
Disease progression (677)
Diarrhoea (631)
Vomiting (600)
Fatigue (419)
Off label use (353)
Dyspnoea (352)
Visual impairment (315)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which CRIZOTINIB Alternatives Have Lower Hepatic cytolysis Risk?
CRIZOTINIB vs CROFELEMER
CRIZOTINIB vs CROMOLYN
CRIZOTINIB vs CROTALIDAE POLYVALENT IMMUNE FAB
CRIZOTINIB vs CUBICIN
CRIZOTINIB vs CUPRIC