Does CRIZOTINIB Cause Large intestine perforation? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Large intestine perforation have been filed in association with CRIZOTINIB (Xalkori). This represents 0.1% of all adverse event reports for CRIZOTINIB.
9
Reports of Large intestine perforation with CRIZOTINIB
0.1%
of all CRIZOTINIB reports
2
Deaths
7
Hospitalizations
How Dangerous Is Large intestine perforation From CRIZOTINIB?
Of the 9 reports, 2 (22.2%) resulted in death, 7 (77.8%) required hospitalization, and 4 (44.4%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CRIZOTINIB. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does CRIZOTINIB Cause?
Death (2,028)
Neoplasm progression (1,161)
Nausea (820)
Disease progression (677)
Diarrhoea (631)
Vomiting (600)
Fatigue (419)
Off label use (353)
Dyspnoea (352)
Visual impairment (315)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which CRIZOTINIB Alternatives Have Lower Large intestine perforation Risk?
CRIZOTINIB vs CROFELEMER
CRIZOTINIB vs CROMOLYN
CRIZOTINIB vs CROTALIDAE POLYVALENT IMMUNE FAB
CRIZOTINIB vs CUBICIN
CRIZOTINIB vs CUPRIC