Does CYCLOSPORINE Cause Splenomegaly? 141 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 141 reports of Splenomegaly have been filed in association with CYCLOSPORINE (Verkazia). This represents 0.2% of all adverse event reports for CYCLOSPORINE.
141
Reports of Splenomegaly with CYCLOSPORINE
0.2%
of all CYCLOSPORINE reports
68
Deaths
63
Hospitalizations
How Dangerous Is Splenomegaly From CYCLOSPORINE?
Of the 141 reports, 68 (48.2%) resulted in death, 63 (44.7%) required hospitalization, and 8 (5.7%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYCLOSPORINE. However, 141 reports have been filed with the FAERS database.
What Other Side Effects Does CYCLOSPORINE Cause?
Drug ineffective (11,172)
Off label use (6,860)
Eye irritation (5,806)
Product use in unapproved indication (5,019)
Condition aggravated (2,310)
Eye pain (2,197)
Drug intolerance (2,176)
Pneumonia (2,022)
Pyrexia (2,020)
Treatment failure (1,961)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which CYCLOSPORINE Alternatives Have Lower Splenomegaly Risk?
CYCLOSPORINE vs CYCLOSPORINE A
CYCLOSPORINE vs CYMBALTA
CYCLOSPORINE vs CYNODON DACTYLON POLLEN
CYCLOSPORINE vs CYPROHEPTADINE
CYCLOSPORINE vs CYPROTERONE