Does CYTARABINE Cause Hypertransaminasaemia? 66 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Hypertransaminasaemia have been filed in association with CYTARABINE (cytarabine). This represents 0.2% of all adverse event reports for CYTARABINE.
66
Reports of Hypertransaminasaemia with CYTARABINE
0.2%
of all CYTARABINE reports
5
Deaths
42
Hospitalizations
How Dangerous Is Hypertransaminasaemia From CYTARABINE?
Of the 66 reports, 5 (7.6%) resulted in death, 42 (63.6%) required hospitalization, and 8 (12.1%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 66 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which CYTARABINE Alternatives Have Lower Hypertransaminasaemia Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB