Does CYTARABINE Cause Necrosis? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Necrosis have been filed in association with CYTARABINE (cytarabine). This represents 0.1% of all adverse event reports for CYTARABINE.
41
Reports of Necrosis with CYTARABINE
0.1%
of all CYTARABINE reports
13
Deaths
27
Hospitalizations
How Dangerous Is Necrosis From CYTARABINE?
Of the 41 reports, 13 (31.7%) resulted in death, 27 (65.9%) required hospitalization, and 1 (2.4%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
Yes, Necrosis is listed as a known adverse reaction in the official FDA drug label for CYTARABINE.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which CYTARABINE Alternatives Have Lower Necrosis Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB