Does CYTARABINE Cause Splenomegaly? 77 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 77 reports of Splenomegaly have been filed in association with CYTARABINE (cytarabine). This represents 0.2% of all adverse event reports for CYTARABINE.
77
Reports of Splenomegaly with CYTARABINE
0.2%
of all CYTARABINE reports
22
Deaths
32
Hospitalizations
How Dangerous Is Splenomegaly From CYTARABINE?
Of the 77 reports, 22 (28.6%) resulted in death, 32 (41.6%) required hospitalization, and 12 (15.6%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 77 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which CYTARABINE Alternatives Have Lower Splenomegaly Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB