Does DABRAFENIB Cause Hepatic cytolysis? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Hepatic cytolysis have been filed in association with DABRAFENIB (Tafinlar). This represents 0.3% of all adverse event reports for DABRAFENIB.
49
Reports of Hepatic cytolysis with DABRAFENIB
0.3%
of all DABRAFENIB reports
3
Deaths
21
Hospitalizations
How Dangerous Is Hepatic cytolysis From DABRAFENIB?
Of the 49 reports, 3 (6.1%) resulted in death, 21 (42.9%) required hospitalization, and 5 (10.2%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DABRAFENIB. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does DABRAFENIB Cause?
Pyrexia (3,788)
Death (2,740)
Malignant neoplasm progression (1,667)
Fatigue (1,328)
Nausea (1,300)
Chills (1,235)
Rash (1,078)
Vomiting (907)
Diarrhoea (901)
Headache (697)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which DABRAFENIB Alternatives Have Lower Hepatic cytolysis Risk?
DABRAFENIB vs DABRAFENIB\TRAMETINIB
DABRAFENIB vs DACARBAZINE
DABRAFENIB vs DACLATASVIR
DABRAFENIB vs DACLIZUMAB
DABRAFENIB vs DACOMITINIB