Does DEFERASIROX Cause Splenomegaly? 108 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 108 reports of Splenomegaly have been filed in association with DEFERASIROX (Deferasirox). This represents 1.0% of all adverse event reports for DEFERASIROX.
108
Reports of Splenomegaly with DEFERASIROX
1.0%
of all DEFERASIROX reports
31
Deaths
63
Hospitalizations
How Dangerous Is Splenomegaly From DEFERASIROX?
Of the 108 reports, 31 (28.7%) resulted in death, 63 (58.3%) required hospitalization, and 16 (14.8%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 108 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which DEFERASIROX Alternatives Have Lower Splenomegaly Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX