Does DENOSUMAB Cause Hyperkeratosis? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Hyperkeratosis have been filed in association with DENOSUMAB (Bilprevda). This represents 0.0% of all adverse event reports for DENOSUMAB.
25
Reports of Hyperkeratosis with DENOSUMAB
0.0%
of all DENOSUMAB reports
2
Deaths
6
Hospitalizations
How Dangerous Is Hyperkeratosis From DENOSUMAB?
Of the 25 reports, 2 (8.0%) resulted in death, 6 (24.0%) required hospitalization.
Is Hyperkeratosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DENOSUMAB. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Hyperkeratosis?
CABOZANTINIB S-MALATE (411)
ADALIMUMAB (332)
SUNITINIB MALATE (170)
ETANERCEPT (168)
SORAFENIB (150)
METHOTREXATE (149)
VEMURAFENIB (145)
REGORAFENIB (136)
RIPRETINIB (124)
RITUXIMAB (121)
Which DENOSUMAB Alternatives Have Lower Hyperkeratosis Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE