Does DICLOFENAC Cause Large intestine perforation? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Large intestine perforation have been filed in association with DICLOFENAC (Diclofenac Sodium Delayed Release). This represents 0.1% of all adverse event reports for DICLOFENAC.
70
Reports of Large intestine perforation with DICLOFENAC
0.1%
of all DICLOFENAC reports
11
Deaths
39
Hospitalizations
How Dangerous Is Large intestine perforation From DICLOFENAC?
Of the 70 reports, 11 (15.7%) resulted in death, 39 (55.7%) required hospitalization, and 19 (27.1%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DICLOFENAC. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does DICLOFENAC Cause?
Drug ineffective (24,885)
Product use in unapproved indication (12,197)
Off label use (10,370)
Pain (9,276)
Product use issue (8,009)
Fatigue (7,908)
Rash (7,852)
Rheumatoid arthritis (7,366)
Abdominal discomfort (7,257)
Product administered at inappropriate site (6,919)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which DICLOFENAC Alternatives Have Lower Large intestine perforation Risk?
DICLOFENAC vs DICLOFENAC DIETHYLAMINE
DICLOFENAC vs DICLOFENAC EPOLAMINE
DICLOFENAC vs DICLOFENAC\DICLOFENAC
DICLOFENAC vs DICLOFENAC\MISOPROSTOL
DICLOFENAC vs DICLOXACILLIN