Does DOXORUBICIN Cause Splenomegaly? 153 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 153 reports of Splenomegaly have been filed in association with DOXORUBICIN (Doxorubicin Hydrochloride). This represents 0.2% of all adverse event reports for DOXORUBICIN.
153
Reports of Splenomegaly with DOXORUBICIN
0.2%
of all DOXORUBICIN reports
35
Deaths
68
Hospitalizations
How Dangerous Is Splenomegaly From DOXORUBICIN?
Of the 153 reports, 35 (22.9%) resulted in death, 68 (44.4%) required hospitalization, and 37 (24.2%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOXORUBICIN. However, 153 reports have been filed with the FAERS database.
What Other Side Effects Does DOXORUBICIN Cause?
Febrile neutropenia (8,844)
Off label use (7,858)
Disease progression (6,165)
Neutropenia (5,891)
Drug ineffective (4,598)
Pyrexia (3,697)
Thrombocytopenia (3,638)
Anaemia (3,601)
Product use in unapproved indication (3,502)
Nausea (2,925)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which DOXORUBICIN Alternatives Have Lower Splenomegaly Risk?
DOXORUBICIN vs DOXYCYCLINE
DOXORUBICIN vs DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYCYCLINE\DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYLAMINE
DOXORUBICIN vs DOXYLAMINE\PYRIDOXINE