Does DURVALUMAB Cause Large intestine perforation? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Large intestine perforation have been filed in association with DURVALUMAB (IMFINZI). This represents 0.1% of all adverse event reports for DURVALUMAB.
20
Reports of Large intestine perforation with DURVALUMAB
0.1%
of all DURVALUMAB reports
8
Deaths
13
Hospitalizations
How Dangerous Is Large intestine perforation From DURVALUMAB?
Of the 20 reports, 8 (40.0%) resulted in death, 13 (65.0%) required hospitalization, and 14 (70.0%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DURVALUMAB. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does DURVALUMAB Cause?
Death (2,817)
Malignant neoplasm progression (1,330)
Pneumonitis (827)
Radiation pneumonitis (786)
Pyrexia (573)
Diarrhoea (530)
Pneumonia (453)
Dyspnoea (444)
Interstitial lung disease (430)
Off label use (395)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which DURVALUMAB Alternatives Have Lower Large intestine perforation Risk?
DURVALUMAB vs DUTASTERIDE
DURVALUMAB vs DUTASTERIDE\TAMSULOSIN
DURVALUMAB vs DUVELISIB
DURVALUMAB vs DYDROGESTERONE
DURVALUMAB vs EBASTINE