Does ESTRADIOL Cause Depression? 328 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 328 reports of Depression have been filed in association with ESTRADIOL (Estradiol). This represents 1.1% of all adverse event reports for ESTRADIOL.
328
Reports of Depression with ESTRADIOL
1.1%
of all ESTRADIOL reports
8
Deaths
46
Hospitalizations
How Dangerous Is Depression From ESTRADIOL?
Of the 328 reports, 8 (2.4%) resulted in death, 46 (14.0%) required hospitalization, and 30 (9.1%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for ESTRADIOL.
What Other Side Effects Does ESTRADIOL Cause?
Product adhesion issue (4,774)
Drug ineffective (4,010)
Off label use (3,238)
Hot flush (2,264)
Wrong technique in product usage process (1,871)
Product quality issue (1,671)
Headache (1,504)
No adverse event (1,493)
Application site pruritus (1,181)
Application site erythema (1,117)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which ESTRADIOL Alternatives Have Lower Depression Risk?
ESTRADIOL vs ESTRADIOL CYPIONATE
ESTRADIOL vs ESTRADIOL\LEVONORGESTREL
ESTRADIOL vs ESTRADIOL\NORETHINDRONE
ESTRADIOL vs ESTRADIOL\NORETHINDRONE\RELUGOLIX
ESTRADIOL vs ESTRADIOL\PROGESTERONE