Does ESTRADIOL Cause Hepatic failure? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Hepatic failure have been filed in association with ESTRADIOL (Estradiol). This represents 0.1% of all adverse event reports for ESTRADIOL.
18
Reports of Hepatic failure with ESTRADIOL
0.1%
of all ESTRADIOL reports
9
Deaths
11
Hospitalizations
How Dangerous Is Hepatic failure From ESTRADIOL?
Of the 18 reports, 9 (50.0%) resulted in death, 11 (61.1%) required hospitalization, and 15 (83.3%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ESTRADIOL. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does ESTRADIOL Cause?
Product adhesion issue (4,774)
Drug ineffective (4,010)
Off label use (3,238)
Hot flush (2,264)
Wrong technique in product usage process (1,871)
Product quality issue (1,671)
Headache (1,504)
No adverse event (1,493)
Application site pruritus (1,181)
Application site erythema (1,117)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which ESTRADIOL Alternatives Have Lower Hepatic failure Risk?
ESTRADIOL vs ESTRADIOL CYPIONATE
ESTRADIOL vs ESTRADIOL\LEVONORGESTREL
ESTRADIOL vs ESTRADIOL\NORETHINDRONE
ESTRADIOL vs ESTRADIOL\NORETHINDRONE\RELUGOLIX
ESTRADIOL vs ESTRADIOL\PROGESTERONE