Does ETOPOSIDE Cause Splenomegaly? 111 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 111 reports of Splenomegaly have been filed in association with ETOPOSIDE (Avopef). This represents 0.2% of all adverse event reports for ETOPOSIDE.
111
Reports of Splenomegaly with ETOPOSIDE
0.2%
of all ETOPOSIDE reports
31
Deaths
68
Hospitalizations
How Dangerous Is Splenomegaly From ETOPOSIDE?
Of the 111 reports, 31 (27.9%) resulted in death, 68 (61.3%) required hospitalization, and 37 (33.3%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 111 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which ETOPOSIDE Alternatives Have Lower Splenomegaly Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS