Does FLUOROURACIL Cause Aplasia? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Aplasia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
55
Reports of Aplasia with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
21
Deaths
28
Hospitalizations
How Dangerous Is Aplasia From FLUOROURACIL?
Of the 55 reports, 21 (38.2%) resulted in death, 28 (50.9%) required hospitalization, and 16 (29.1%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which FLUOROURACIL Alternatives Have Lower Aplasia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE