Does FLUOROURACIL Cause Hepatic failure? 214 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 214 reports of Hepatic failure have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.4% of all adverse event reports for FLUOROURACIL.
214
Reports of Hepatic failure with FLUOROURACIL
0.4%
of all FLUOROURACIL reports
134
Deaths
97
Hospitalizations
How Dangerous Is Hepatic failure From FLUOROURACIL?
Of the 214 reports, 134 (62.6%) resulted in death, 97 (45.3%) required hospitalization, and 38 (17.8%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 214 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which FLUOROURACIL Alternatives Have Lower Hepatic failure Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE