Does GLIVEC Cause Splenomegaly? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Splenomegaly have been filed in association with GLIVEC. This represents 1.0% of all adverse event reports for GLIVEC.
10
Reports of Splenomegaly with GLIVEC
1.0%
of all GLIVEC reports
4
Deaths
3
Hospitalizations
How Dangerous Is Splenomegaly From GLIVEC?
Of the 10 reports, 4 (40.0%) resulted in death, 3 (30.0%) required hospitalization, and 1 (10.0%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GLIVEC. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does GLIVEC Cause?
Death (628)
Malignant neoplasm progression (60)
Gastrointestinal stromal tumour (40)
Chronic myeloid leukaemia (38)
Anaemia (30)
Second primary malignancy (27)
Pyrexia (21)
Blast crisis in myelogenous leukaemia (20)
Dyspnoea (19)
Malaise (16)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which GLIVEC Alternatives Have Lower Splenomegaly Risk?
GLIVEC vs GLOFITAMAB
GLIVEC vs GLOFITAMAB-GXBM
GLIVEC vs GLUCAGON
GLIVEC vs GLUCAGON\GLUCAGON\WATER
GLIVEC vs GLUCARPIDASE